Detroit opens the season a massive home favorite, but this isn't the same Lions team that ran off back-to-back division titles — and New Orleans is bringing a rebuilt offense and a QB with something to prove.
Bush’s PicksPicks madeJul 7, 1:11 PM CT
+275NODET-332
+111NO +6.5DET -6.5-126
-108Over 49.5Under 49.5-108
Best BetLions -332
Detroit's price reflects a real gap in overall roster talent even accounting for a down 2025 — Gibbs, St. Brown and a retooled pass rush give the Lions more paths to a win than a Saints team still answering questions about its receiver room. New Orleans' rookie-QB breakout is real, but it's not enough on its own to make this a true coinflip. Lay the number and back Detroit at home in the opener.
Saints
+Shough was OROY runner-up after midseason takeover
+Added Etienne and Tyson to loaded skill corps
+Finished 2025 winning 4 of last 5
−Still finished 6-11, defense retooled with unproven names
−Olave dealt with illness while seeking new contract
−Rookie WR Tyson limited in offseason workouts
Lions
+9-8 roster still has Gibbs, St. Brown, elite talent
+Gibbs named the team's clear bellcow back for 2026
+Added pass-rush help (Wonnum) around Hutchinson
−Missed playoffs after two straight division titles
−LaPorta's back injury status unresolved for camp
−Conservative free-agency spend raises Super Bowl-window questions
Sunday, September 13 at Ford Field is Tyler Shough's first game as a true QB1. He grabbed the job midseason as a rookie, closed the year as the Offensive Rookie of the Year runner-up, and now gets a full offseason worth of continuity with Kellen Moore calling plays. On the other side, Jared Goff and the Lions are trying to prove last year's stumble was a blip, not the start of a decline — with a wide receiver room and backfield that still looks like one of the best in the league on paper.
New Orleans didn't sit on its hands after Shough's strong finish. The Saints handed Travis Etienne a four-year deal to pair with Alvin Kamara, and used premium draft capital on Jordyn Tyson to give Shough a true WR2 next to Chris Olave. The concern is health and continuity everywhere else — Olave has dealt with an illness this offseason while working toward a new contract, and Tyson himself has been limited in camp workouts. Detroit's version of that story is Sam LaPorta, who's working back from a herniated disc that ended his 2025 season; coach Dan Campbell says he's trending toward being ready, but it's not locked in.
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Jahmyr Gibbs enters the year as the unquestioned bellcow back after Campbell all but said as much this spring, and Amon-Ra St. Brown looks like his usual dominant self heading into camp. That's still a load for a Saints defense that's been retooling on the fly with a wave of low-profile free-agent additions. Detroit, for its part, spent its offseason more conservatively than usual, adding pass-rush help like D.J. Wonnum around Aidan Hutchinson rather than making a splash — a sign the front office is picking its spots rather than chasing last year back all at once.
New Orleans Saints
Aug 28?@ Cowboys—
Aug 22?@ Rams—
Aug 15?vs Jaguars—
Detroit Lions
Aug 29?@ Colts—
Aug 22?vs Commanders—
Aug 13?@ Bengals—
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It's worth noting how each team actually finished 2025. New Orleans won 4 of its last 5 before a late loss to Atlanta, riding Shough's development. Detroit did the opposite — dropping three of four before salvaging the finale against Chicago — the kind of malaise that turned a two-time division winner into a 9-8 team watching the playoffs from home. None of that guarantees anything about Week 1, but it's the backdrop for why Detroit isn't the runaway juggernaut it was two years ago, even at nearly 3-to-1 on the moneyline.
New Orleans Saints
(0)
Fully healthy — no injuries on ESPN's report
Detroit Lions
(0)
Fully healthy — no injuries on ESPN's report
Injury report — info via ESPN.
For a season opener, this one has real stakes attached beyond just three points. It's a measuring-stick game for a Saints offense that thinks it's turned a corner, and a get-right spot for a Lions team that knows the margin for error just got a lot smaller.