DEN to win-100TLDR: Denver gets a Rams team without Myles Garrett, coming off a Monday game into a Sunday night at 5,280 feet, and the Broncos have not lost to an NFC team since 2024.
Point
- Pass rush
Myles Garrett had knee surgery and is on injured reserve through Week 5, so the Rams face Nix without the reigning Defensive Player of the Year.
- Rest
The Rams beat the Giants on Monday night at SoFi and get 6 days before kickoff, while Denver had 7 after winning at home on Sunday.
- Venue
Only 1 team, Jacksonville, won at Empower Field in the 2025 regular season, and visitors play at 5,280 feet one week removed from a Monday game.
- Cross-conference
Denver has won 9 straight against NFC teams since Week 1 of 2024, and Nix is 9-1 against the NFC with the loss in his first start.
Counterpoint
- Rams vs AFC
The Rams have won 8 straight against AFC opponents since a Week 10 loss to Miami in 2024, so their streak is almost as long as Denver's.
- Secondary
The Rams added cornerback Trent McDuffie this offseason, which gives them a No. 1 corner to put on Waddle, something Jacksonville did not have.
Neutral
- Aaron Donald
Donald, 35, sat out Friday's practice for rest and has no designation, so he plays, though the team is managing his workload in his 2nd game back.
- Weather
Kickoff is 6:20 PM MT in an open stadium with mild, dry conditions forecast, so weather should not slow either passing game.