Clemson Tigers at LSU Tigers

Sep 5, 20266:30 PM CT
By JR·2 min read
Clemson
#15 LSU
10—51
FINAL

TLDR: Lane Kiffin gets his first look at a packed Tiger Stadium, and Clemson gets to be the team standing in the doorway. Two blue bloods trying to prove last season was the fluke, in front of the most credentialed crowd this building has ever seen.

FINAL · SAT SEP 5, 11:30 PM
10
51
Final1Q2Q3Q4QT
CLEM
300710
LSU
171413751
Clemson Tigers
  • Skill starters Wesco Jr., Moore, Patt-Henry all healthy
  • Two returning starters back up front
  • Vizzina has 71 career snaps in his only start, a loss
  • Left off AP poll, coming off worst season since 2010
  • Lost 9 players to the NFL Draft
LSU Tigers
  • Sam Leavitt led ASU to a Big 12 title, CFP berth in 2024
  • Record-hyped home crowd for Kiffin's Tiger Stadium debut
  • Trey'Dez Green a proven weapon at tight end
  • Leavitt missed the final month of 2025 with a foot injury
  • No returning starter continuity after Nussmeier's exit
  • First game in a brand-new system under a first-year staff

Neither team is trotting out the quarterback that started last year's meeting. Garrett Nussmeier is off to the NFL after an oblique injury cut into his final LSU season, and Cade Klubnik's gone from Clemson too. In his place, LSU handed the job to Arizona State transfer Sam Leavitt, the No. 1-ranked quarterback to hit the portal, a dual-threat who led the Sun Devils to a Big 12 title and a College Football Playoff berth in 2024. Clemson's answer is Cade's understudy: Sam Vizzina was only named the starter days before kickoff, a fourth-year player who's barely played.

That inexperience is the whole story for Clemson right now. Vizzina has taken 238 offensive snaps in his career, with 71 of those coming in his lone start, a loss to SMU. The Tigers do have their weapons back healthy for him to lean on — receivers Bryant Wesco Jr. and T.J. Moore, tight end Olsen Patt-Henry and a pair of returning starters up front all cleared for Baton Rouge — which is more than last year's group could say. The number reflects the gap: Clemson's the road underdog by nearly two touchdowns.

The circus around this one is real. Kiffin left Ole Miss for a $91 million deal to rebuild LSU, spent his offseason in the middle of an eligibility fight that pulled in the SEC and the NFL, and now gets his first walk into Tiger Stadium as the man in charge. LSU issued a record number of media credentials for it, College GameDay is setting up in Baton Rouge, and Kiffin himself compared the night to a concert. The total's been bet down some since the board opened, which tracks with a game carrying two new starting quarterbacks nobody's fully seen live yet.

Clemson's not walking in confident on the whole. The Tigers were left off the AP's preseason poll for the first time since 2011 after finishing 7-6, Dabo Swinney's worst mark since 2010, and they lost nine players to the NFL Draft off that roster. Coaches still have them ranked in the 20s, which is either residual respect for the program or a poll that hasn't caught up — Saturday starts answering that.

LSU's not without its own question marks even with the hype. Leavitt missed the final month of his 2025 season at Arizona State with a foot injury, so this is effectively his first extended live look since. Trey'Dez Green gives him a proven target at tight end, and the crowd Kiffin's built up all preseason should be as loud as Tiger Stadium gets. Whether either quarterback looks the part on a stage this big is the whole night.

Clemson 10, LSU 51: Final Score & Odds Recap — Clemson Walks Into Kiffin's Wild LSU Debut In Death Valley