Colorado Buffaloes at Oklahoma State Cowboys

Fresh Starts Collide As Colorado Visits Oklahoma State's New Era

By Pablo SanchezUpdated 6d ago·2 min read
Colorado BuffaloesCOLO
Oklahoma State CowboysOKST
AT
11:00 PM CT
Bush’s Picks
COLOOKST
COLOOKST
OverUnder
Best BetOklahoma State

Oklahoma State brings a completely retooled roster and a coach with a track record of scoring points, which is enough to lean home here even against a Colorado team that's spent all offseason talking about turning the corner. The Cowboys' offensive talent infusion, led by Mestemaker, gives them a higher ceiling than a Colorado group still settling its quarterback room.

Colorado
  • Julian Lewis threw 0 interceptions as a freshman starter
  • As many as 11 new defensive starters
  • Sanders publicly confident after tough 2025
  • Finished 3-9 last season
  • Lost Travis Hunter and Shedeur Sanders to NFL
  • Quarterback battle still not settled
Oklahoma State
  • Eric Morris went 11-2 at North Texas
  • Imported nation's leading passer in Mestemaker
  • Massive 62-player transfer portal infusion
  • Finished 1-11, winless in Big 12 play
  • Fired Gundy just 3 games into 2025
  • Secondary is a major unknown

Colorado's quarterback room is still sorting itself out heading into the season, with redshirt freshman Julian Lewis holding the edge over Utah transfer Isaac Wilson. Lewis started 2 games as a true freshman in 2025, completing 52-of-94 passes for 589 yards, 4 touchdowns and 0 interceptions, and Deion Sanders has made no secret of his expectations, telling reporters at Big 12 Media Days simply, 'We're going to win.' Across the field, Oklahoma State handed the keys to new head coach Eric Morris, who arrives after leading North Texas to an 11-2 record, and brought his quarterback with him.

Morris didn't just import a coordinator's playbook — he gutted the roster. Oklahoma State added more than 80 new players this offseason, 62 of them via the transfer portal, headlined by Drew Mestemaker, who led the country in passing yards a season ago with 4,379 yards and 34 touchdowns against just 9 interceptions at North Texas. Colorado's response was a defensive overhaul of its own, with as many as 11 new starters expected on that side of the ball after a season that exposed just how thin the roster got once Travis Hunter and Shedeur Sanders left for the NFL.

Neither of these programs is walking in with anything to protect. Colorado finished 3-9 in 2025, and Oklahoma State was worse, going 1-11 and 0-9 in Big 12 play after firing Mike Gundy just 3 games into his 21st season. This is a Friday night matchup between 2 staffs trying to prove their offseason overhaul actually took, and that alone makes it worth a look even before either team plays a snap that counts against this one.

The style clash here is real. Morris wants to push tempo behind Mestemaker's arm and a backfield led by rushing touchdown leader Caleb Hawkins, while Colorado is banking on a retooled defensive front to slow things down before its own offense finds its footing under new offensive coordinator Brennan Marion. If Oklahoma State's secondary is as unsettled as it looked in preseason chatter, that's the matchup Colorado's passing game will try to exploit.

Colorado Buffaloes
Colorado Buffaloes
(0)
Fully healthy — no injuries on ESPN's report
Oklahoma State Cowboys
Oklahoma State Cowboys
(0)
Fully healthy — no injuries on ESPN's report
Injury report — info via ESPN.

Whichever team leaves Stillwater with a win gets a real building block for its rebuild; the loser is right back to answering questions about whether the offseason changes were enough. That's the actual stakes of a game between 2 teams picking themselves up off the floor.

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