- Day-To-DayWalker Janek (C) — Double-A Corpus Christi placed Janek on its 7-day injured list Sunday due to an unspecified injury.05/08
- 10-Day-ILJake Meyers (CF) — Meyers (oblique) will join the Astros in Minneapolis and is slated to be activated from the 10-day injured list during the series against the Twins, Chandler Rome of The Athletic reports.05/18
- 10-Day-ILJose Altuve (2B) — The Astros placed Altuve on the 10-day injured list Monday with a left oblique strain.05/18
- 10-Day-ILCarlos Correa (SS) — Correa is scheduled to undergo surgery Monday in Houston to repair the tendon in his left ankle, Brian McTaggart of MLB.com reports.05/10
- 10-Day-ILJoey Loperfido (LF) — The Astros announced Monday that Loperfido (quadriceps) has started light running and light baseball activity, Matt Kawahara of the Houston Chronicle reports.05/08
- 10-Day-ILTaylor Trammell (CF) — The Astros announced Monday that Trammell (groin) has begun a running progression in addition to taking part in light baseball activity, Matt Kawahara of the Houston Chronicle reports.05/08
- 10-Day-ILYainer Diaz (C) — The Astros placed Diaz (oblique) on the 10-day injured list Tuesday, Brian McTaggart of MLB.com reports.05/08
- 15-Day-ILNate Pearson (RP) — Pearson (elbow) could be activated from the 15-day injured list during Houston's series against Minnesota, Matt Kawahara of the Houston Chronicle reports.05/19
- 15-Day-ILBennett Sousa (RP) — The Astros placed Sousa on the 15-day injured list Saturday with left elbow inflammation, retroactive to Wednesday, Julia Morales of Space City Home Network reports.05/09
- 60-Day-ILHunter Brown (SP) — GM Dana Brown said Brown (shoulder) will throw live batting practice Tuesday before potentially beginning a rehab assignment, with the Astros targeting mid-June to activate him from the injured list, Chandler Rome of The Athletic reports.05/17
- 60-Day-ILJosh Hader (RP) — Astros manager Joe Espada said Saturday that Hader (biceps) will log at least five more rehab appearances before he's activated from the 60-day injured list, Chandler Rome of The Athletic reports.05/16
- 60-Day-ILHayden Wesneski (SP) — The Astros announced Monday that Wesneski (elbow) is continuing to complete regular bullpen sessions as part of his throwing progression, Matt Kawahara of the Houston Chronicle reports.05/08
- 60-Day-ILRonel Blanco (SP) — The Astros announced Monday that Blanco (elbow) is continuing to complete regular bullpen sessions as part of his throwing progression, Matt Kawahara of the Houston Chronicle reports.05/08
- 60-Day-ILBrandon Walter (SP) — The Astros placed Walter (elbow) on the 60-day injured list.05/08
- 60-Day-ILCristian Javier (SP) — The Astros announced Monday that Javier (shoulder) will begin a throwing progression this week, Matt Kawahara of the Houston Chronicle reports.05/08
- Day-To-DayRyan Jeffers (C) — Jeffers left Monday's game against Houston with a left wrist sprain, Aaron Gleeman of AaronGleeman.com reports.05/19
- Day-To-DayByron Buxton (CF) — Buxton (hip) is out of the lineup for Monday's game against the Astros.05/18
- Day-To-DayWalker Jenkins (CF) — Twins manager Jeremy Zoll said Saturday that Jenkins (shoulder) is "reporting improvements daily" and could begin light baseball activity in about a week, Bobby Nightengale of The Minnesota Star Tribune reports.05/18
- Day-To-DayCory Lewis (SP) — Twins head trainer Nick Paparesta said Thursday that Lewis (shoulder) is still a couple weeks away from throwing off a mound, Bobby Nightengale of The Minnesota Star Tribune reports.05/08
- Day-To-DayJulian Merryweather (RP) — Merryweather (hamstring) will begin a rehab assignment with the Twins' rookie-level Florida Complex League affiliate Tuesday, Theodore Tollefson of ZoneCoverage.com reports.05/08
- Day-To-DayMatt Canterino (SP) — Canterino (shoulder) will be with the Twins in big-league spring training but isn't expected to pitch during camp as he continues to recover from shoulder surgery, Aaron Gleeman of The Athletic reports.05/08
- 15-Day-ILCole Sands (RP) — Twins general manager Jeremy Zoll said that Sands (forearm) played catch on consecutive days last week and is expected to spend about a month on the injured list, Bobby Nightengale of The Minnesota Star Tribune reports.05/18
- 15-Day-ILMick Abel (SP) — Abel (elbow/triceps) resumed playing light catch Wednesday, Bobby Nightengale of The Minnesota Star Tribune reports.05/18
- 15-Day-ILCody Laweryson (RP) — Laweryson (forearm) worked around a walk to deliver a scoreless inning in his rehab appearance Saturday with Triple-A St. Paul.05/18
- 15-Day-ILTaj Bradley (SP) — Bradley (pectoral) struck out three and allowed one earned run on two hits and two walks across 1.2 innings in a rehab start Sunday for Triple-A St. Paul.05/18
- 15-Day-ILGarrett Acton (RP) — The Twins placed Acton on the 15-day injured list Tuesday with a right shoulder strain, Dan Hayes of The Athletic reports.05/08
- 60-Day-ILDavid Festa (SP) — Twins general manager Jeremy Zoll said Saturday that Festa is unlikely to return before the All-Star break after experiencing a setback in his recovery from a right shoulder impingement earlier this month, Bobby Nightengale of The Minnesota Star Tribune reports.05/18
- 60-Day-ILPablo Lopez (SP) — The Twins placed Lopez (elbow) on the 60-day injured list Thursday.05/08
McCullers takes the ball at 2-3 with a 6.86 ERA, and Houston needs length out of him more than anything else with the bullpen this thin. He did show signs of life earlier this month — a strong outing against the Dodgers got people thinking the version from years ago might be hiding in there somewhere — but the season-long line still says hitters are teeing off.
Minnesota counters with Zebby Matthews, who threw 7 scoreless against Miami in his season debut on May 14 (4 hits, 1 walk, 5 K). That's the only data point on his 2026 ledger, hence the 0.00 ERA next to his name. Small sample, sure, but a fresh arm against a banged-up Astros lineup that just lost its second baseman is the kind of edge the Twins have been waiting for.
The Twins aren't exactly humming either — 22-26, with Byron Buxton out (hip) and Ryan Jeffers leaving Monday's game with a wrist sprain. But they've won 3 of their last 5, and the market clearly likes them tonight: Pinnacle has Minnesota at -135 with positive EV on the moneyline, and the public is on the same side at DK (77% of handle, 61% of bets on the Twins ML).
Total sits at 8.5 on Pinnacle and 9 on DK, which feels honest given Matthews's profile and McCullers's volatility — one mistake inning from Lance and we're racing to the over by the 5th. If you trust the Matthews debut and the Astros' walking-wounded lineup, the under is the cleaner read. If you don't, this game gets ugly in a hurry.