Chicago Cubs at Chicago White Sox

Crosstown Classic Opens With Cubs Trying to Outrun the South Side Buzzsaw

By Pablo SanchezUpdated 53d ago·2 min read
6:40 PM CT
Chicago CubsCHC(28-16)
Chicago White SoxCWS(22-21)
105
FINAL
123456789RHE
CHC
10012024010140
CWS
010021001580
Final box score — data via ESPN.
Chicago Cubs
Edward Cabrera
(3-2)·4.00 ERA
May 20 vs Brewers
L
3.0IP
1ER
2K
2BB
61P
Chicago White Sox
Sean Burke
(2-3)·3.90 ERA
May 26 vs Twins
ND
7.0IP
2ER
8K
2BB
100P
On the mound — starting pitchers.

Cubs at White Sox, Rate Field, Friday night. The North Siders are still sitting on the better record at 28-16, but they limped into this weekend on a 4-game skid that was finally snapped Thursday with a 2-0 shutout of the Braves behind Ian Happ's solo shot. The Sox, meanwhile, swept the Royals to push their win streak to 5 and crossed .500 for the first time since 2022.

Chicago Cubs
Chicago Cubs
(28-16)
LLLLW
Chicago White Sox
Chicago White Sox
(22-21)
WWWWW
Recent form.

Edward Cabrera (3-1, 3.88) gets the ball for the Cubs and the underlying stuff is nasty, but the home run ball has been a problem — 7 of them across his last 4 starts. Sean Burke counters at 2-3 with a 3.68 ERA, though his most recent outing was a 6-run, 4.1-inning beating in Seattle. Two arms who can absolutely dominate, both coming off starts that should have them annoyed.

The market sees this as a Cubs game. Cabrera's team is favored at -146 on the moneyline, the run line has Chicago laying 1.5, and the total sits at a fairly tight 8.5. Whether you trust that price given the way these two teams are actually playing right now is a different question.

The Cubs' pitching staff is being held together with duct tape. Justin Steele, Cade Horton, Porter Hodge, Shelby Miller, and Matthew Boyd are all on the shelf, with Steele not expected back until after the All-Star break. Craig Counsell has been mixing and matching for weeks. The White Sox have their own bullpen wear-and-tear, plus Kyle Teel and Austin Hays still rehabbing, but Will Venable's group has clearly figured something out in the last week and a half.

Chicago Cubs
Chicago Cubs
(13)
  • Day-To-DayBrandon Birdsell RPBirdsell (elbow) will miss the entire 2026 season, Jim Callis of MLB Pipeline reports.
  • Day-To-DayJeff Brigham RPBrigham was placed on the 7-day injured list at Triple-A St. Paul, retroactive to April 6, with a left oblique strain, TwinsDaily.com reports.
  • Day-To-DayJaxon Wiggins SPCubs manager Craig Counsell said that Wiggins was placed on Triple-A Iowa's 7-day injured list Wednesday due to right elbow inflammation, Meghan Montemurro of the Chicago Tribune reports.
  • 15-Day-ILHunter Harvey RPHarvey was diagnosed with a stress reaction in his right triceps Friday, Paul Sullivan of the Chicago Tribune reports.
  • 15-Day-ILJordan Wicks RPWicks (elbow) struck out two batters and allowed one hit and one walk over three scoreless innings Saturday in a rehab start for Triple-A Iowa.
  • 15-Day-ILMatthew Boyd SPBoyd underwent a successful menisectomy Thursday, Taylor McGregor of Marquee Sports Network reports.
  • 15-Day-ILRiley Martin RPMartin has been diagnosed with flexor strain in his left elbow and is expected to miss eight weeks, Taylor McGregor of Marquee Sports Network reports.
  • 15-Day-ILCaleb Thielbar RPThe Cubs placed Thielbar on the 15-day injured list Friday with a left hamstring strain.
Chicago White Sox
Chicago White Sox
(11)
  • Day-To-DayMason Adams RPThe White Sox announced that Adams underwent successful Tommy John surgery Wednesday, Scott Merkin of MLB.com reports.
  • 10-Day-ILKyle Teel CTeel (hamstring) will report to Triple-A Charlotte on Tuesday to begin a rehab assignment, LaMond Pope of the Chicago Tribune reports.
  • 10-Day-ILAustin Hays LFManager Will Venable said Saturday that Hays (calf) has resumed taking live batting practice and could begin running the bases next week, Jared Wyllys of AllCHGO.com reports.
  • 10-Day-ILEverson Pereira RFThe White Sox placed Pereira on the 10-day injured list Wednesday due to a right pectoral strain.
  • 60-Day-ILPrelander Berroa RPBerroa (elbow) will begin a rehab assignment Wednesday in the rookie-level Arizona Complex League, Scott Merkin of MLB.com reports.
  • 60-Day-ILMike Vasil RPThe White Sox transferred Vasil (elbow) from the 15-day injured list to the 60-day IL on Tuesday.
  • 60-Day-ILTanner Murray LFThe White Sox transferred Murray (shoulder) to the 60-day injured list Monday.
  • 60-Day-ILBrooks Baldwin LFThe White Sox transferred Baldwin (elbow) from the 10-day injured list to the 60-day IL on Wednesday.
Injury report — info via ESPN.

This is the part of the rivalry where everyone usually pencils the Cubs in and moves on. Not this weekend. The Sox have won 16 of their last 24, Grichuk has been a sneaky pickup since the Yankees released him, and Burke pitching at home in front of a juiced crowd is a different animal than Burke in Seattle. The Cubs are still the more complete roster — but if they sleepwalk into this one, the South Side is more than ready to make them pay.

MLBChicago CubsChicago White SoxPinnaclePolymarketKalshiEdward CabreraSean Burke
Crosstown Classic Opens With Cubs Trying to Outrun the South Side Buzzsaw — Chicago White Sox | Polymarket Odds · Barstool Bush