First pitch is set for 6:40 PM CT at American Family Field, and the pitching matchup is the entire story. Trevor McDonald (2-2, 4.34) gets the ball for the Giants opposite Kyle Harrison, the former San Francisco lefty now putting up a 6-1 record and a 1.57 ERA in Milwaukee. Yes, that Kyle Harrison. Yes, against his old team.
Harrison's 1.57 ERA is the lowest mark by any pitcher in his first 10 starts in Brewers franchise history, ahead of CC Sabathia's 2008 stretch run. The Brewers are 8-2 when he starts and have won seven straight Harrison outings. He's coming off six scoreless against the Cardinals on May 26 with four hits allowed and zero walks. The Giants get him at the worst possible time and on the road, where they've been a tire fire all year.


Monday's opener was as ugly as it gets — Brewers 16, Giants 2, with Milwaukee piling up season-highs in runs and hits (18) without leaving the yard. Brice Turang snapped an 0-for-21 by reaching all four times, Christian Yelich and David Hamilton both went 3-for-5, and Jackson Chourio drove in three. San Francisco has now dropped six of seven and is staring down 23-37 with a road trip that keeps getting heavier.

- 10-Day-ILHeliot Ramos LF — Ramos (quadriceps) will begin a hitting progression at the Giants' spring training complex in Arizona on Monday, Susan Slusser of the San Francisco Chronicle reports.
- 10-Day-ILHarrison Bader CF — Bader isn't in the lineup for Saturday's game against Colorado, Susan Slusser of the San Francisco Chronicle reports.
- 15-Day-ILTyler Mahle SP — The Giants placed Mahle on the 15-day injured list Friday, retroactive to Wednesday, due to a left hamstring strain, Justice delos Santos of The San Jose Mercury News reports.
- 60-Day-ILJoel Peguero RP — The Giants placed Peguero on the 60-day injured list Monday due to a left hamstring strain, John Shea of the San Francisco Chronicle reports.
- 60-Day-ILJared Oliva CF — Oliva (wrist) started at designated hitter and went 2-for-2 with two stolen bases, a double, an RBI and a run scored in Triple-A Sacramento's 6-4 loss to Reno on Saturday.
- 60-Day-ILReiver Sanmartin RP — Sanmartin (hip) tossed a scoreless inning in Triple-A Sacramento's 11-6 win over Sugar Land on Tuesday.
- 60-Day-ILJason Foley RP — Foley (shoulder) earned a hold in Triple-A Sacramento's 6-5 loss to Round Rock on Wednesday, allowing one hit in a scoreless inning.
- 60-Day-ILRowan Wick RP — The Giants placed Wick (elbow) on the 60-day injured list Sunday, Justice delos Santos of The San Jose Mercury News reports.

- Day-To-DayGerson Garabito RP — Garabito will be out for four months after undergoing surgery to address a broken bone in his foot, Todd Rosiak of the Milwaukee Journal Sentinel reports.
- 10-Day-ILBrandon Lockridge LF — Lockridge (knee) will attempt to run at 85-to-90 percent intensity Monday, Adam McCalvy of MLB.com reports.
- 15-Day-ILBrandon Woodruff SP — Woodruff (shoulder) will throw a three-up live batting practice session Wednesday, Adam McCalvy of MLB.com reports.
- 15-Day-ILQuinn Priester SP — Priester (shoulder) recorded two outs and was charged with three earned runs on two hits and three walks Wednesday in his rehab start with Triple-A Nashville. He struck out one batter.
- 15-Day-ILJared Koenig RP — Koenig (elbow) said his live bullpen session went well Tuesday and he expects to begin a rehab assignment with Triple-A Nashville on Friday, Adam McCalvy of MLB.com reports.
- 15-Day-ILLogan Henderson SP — Brewers manager Pat Murphy said Monday that Henderson might not make his next scheduled start Wednesday against the Cardinals due to back tightness, Jack Stern of BrewerFanatic.com reports.
- 60-Day-ILAngel Zerpa RP — The Brewers transferred Zerpa (elbow) to the 60-day injured list Sunday.
The injury board is a big reason the Giants look this thin. Both starting outfielders are out — Heliot Ramos (quad) and Harrison Bader (undisclosed) — and the bullpen is essentially a MASH unit, with Randy Rodriguez, Hayden Birdsong, Rowan Wick, Jose Butto and Jason Foley all on the 60-day. Tyler Mahle hit the 15-day with a hamstring strain last week too. There just isn't a lot of cavalry coming.
Pinnacle has Milwaukee at -207 with a 7.5 total, which feels honest. The Giants need McDonald to do something they didn't get on Monday — keep the early innings clean — and they need to actually make Harrison work a count. The Brewers have done that to him exactly zero times this year. Hard to see this one looking much different than 24 hours ago.