Indianapolis Colts at Kansas City Chiefs

Kansas City, MO
By Bush StaffUpdated 45d ago·2 min read
Indianapolis ColtsIND
Kansas City ChiefsKC
AT
7:20 PM CT

Two teams that both closed 2025 on five-game losing skids meet under the Sunday night lights, and this one doubles as a referendum on two shaky quarterback situations.

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MON SEP 21 · 7:20 PM CT
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Patrick Mahomes tore his ACL and LCL on December 14, 2025, and had surgery the next day — the kind of injury that ends most players' seasons and clouds the start of the next one. He's reportedly ahead of schedule and targeting a Week 1 return, which puts this Week 2 Sunday Night Football date against the Colts squarely in the window where everyone will be watching how his knee actually holds up under game speed.

The Colts have their own quarterback drama, just a different flavor. Daniel Jones is working back from his own Achilles tear and has reportedly been on track throughout the offseason program, trading reps in camp with Anthony Richardson Sr. in a competition Shane Steichen has refused to put a timetable on. Whoever wins that job inherits an offense that still runs through Jonathan Taylor, even as Steichen himself has voiced concern about leaning on his workhorse too hard.

Kansas City spent the spring trying to reload around Mahomes rather than pivot away from him. Travis Kelce re-signed on a three-year deal worth $54.74 million instead of riding into the sunset, and Rashee Rice is back in the fold after a suspension and a 30-day jail stint tied to a probation violation, plus a knee cleanup that briefly threatened his return timeline.

Indianapolis Colts
Indianapolis Colts
Kansas City Chiefs
Kansas City Chiefs

Neither team is walking into this game with much recent momentum. The Chiefs missed the playoffs after a season that unraveled into five straight losses, and the Colts limped to the finish the exact same way — a stretch that included getting outscored 48-27 by San Francisco and 38-30 by Houston. That shared collapse is part of why this early-season measuring-stick game carries more intrigue than the records alone suggest.

Indianapolis Colts
Indianapolis Colts
(0)
Fully healthy — no injuries to report
Kansas City Chiefs
Kansas City Chiefs
(0)
Fully healthy — no injuries to report

Health is the swing factor for both sidelines. Rice and Xavier Worthy are both trending in the right direction after minicamp looks that had Andy Reid encouraged, while George Karlaftis is a reminder Kansas City's defense played through real pain last year — he reportedly worked multiple games on a broken hand. On the Colts' side, Sauce Gardner and a banged-up secondary will be tested early against whichever Chiefs weapons are actually available come kickoff at 7:20 PM CT.

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